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Production of proteins in the cell

Source: University of Michigan School for Environment and Sustainability, www.flickr.com, licencja: CC BY 2.0.

Link to the lesson

Before you start you should know
  • genetic information is stored in DNA;

  • the gene is a fragment of DNA.

You will learn
  • explain how on the basis of DNA produced proteins create certain characteristics of the body;

  • distinguish the terms genetic code and genetic information;

  • show how genetic information is stored in DNA;

  • describe genetic code.

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Nagranie dźwiękowe dotyczące wytwarzania białek w komórce

Proteins are made of amino acids that combine with each other in very long chains. Each protein is characterized by a specific number of amino acids and the order in which they are arranged. The function of protein in the body depends on the aminoacid composition. The type and order of amino acids is determined by the sequence of nucleotides in the gene.

The nucleotides that make up the gene are read in threes. One of the three nucleotides corresponds to one amino acid. The three nucleotides are the basic coding unit in the genetic code, called codoncodoncodon.

The genetic code consists of 64 codons. 61 of them encode amino acids. One of them is a START codon. It determines the amino acid called methionine, from which the synthesis of each protein begins. Three other codons, are called STOP codons, they do not correspond to any amino acid. Their presence is a signal to stop protein production. Such a signal in the form of a codon is necessary because the genetic code contains no gaps or separating characters. If STOP codons did not exist, protein synthesis could go on forever.

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Grafika przedstawia trzy kolumny kodów aminokwasów: A-filoletowe, G-niebieski, C- żółty, T- zielony. Pierwsza kolumna: AGA AGG CGA CGG CGT CGC, druga kolumna: GGA GGG GGT GGC, trzecia kolumna TAT TAC. Nad każdą kolumną są napisy 1. arginine , 2. glycine , 3. tyrosine
What amino acids code the following codons?
Source: GroMar Sp. z o.o., licencja: CC BY-SA 3.0.
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Exercise 1
Wskaż wszystkie kombinacje przedstawiające glicynę zakodowaną przy pomocy różnych kodonów. Możliwe odpowiedzi: 1. GGT, 2. GGA, 3. AGT, 4. CGA
Source: licencja: CC BY-SA 3.0.
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Exercise 2
Wymień nazwy aminokwasów.
Source: GroMar Sp. z o.o., licencja: CC BY-SA 3.0.
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Exercise 3
Ćwiczenie wskaż prawdziwe stwierdzenia. Indicate all true statements. Możliwe odpowiedzi: 1. The proteins are made of amino acids connected in long chains., 2. The number of amino acids and their order in the protein determines its properties., 3. The type and order of amino acids in the protein depend on the order of nucleotides in the gene., 4. Each nucleotide encodes information on one amino acid in the protein.
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Exercise 4
Ćwiczenie wskaż prawidłową odpowiedź. What does the term codon mean? Indicate the correct answer. Możliwe odpowiedzi: 1. a single nucleotide in the DNA sequence coding for one amino acid, 2. three consecutive nucleotides in the DNA sequence coding for one amino acid, 3. a single amino acid encoded by the appropriate nucleotide sequence, 4. an amino acid chain encoded by the appropriate nucleotide sequence

Summary

  • The genetic code is a way of recording information about the structure of proteins.

  • The genetic code is in threes, meaning that one amino acid is coded by three nucleotides called codons.

  • The gene contains information about the structure of a specific protein; the order of codons in the gene determines the order of amino acids in the protein.

  • The genetic code is universal; Genetic information is recorded in all organisms in the same way.

Homework
Task 1.1

Explain the relationship between the gene, protein and body traits.

Keywords

codon, genetic code, nucleotides

Glossary

genetic information
genetic information
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Nagranie dźwiękowe słówka genetic information

informacja genetyczna –- informacja o kolejności aminokwasów w białkach zakodowana w sekwencji nukleotydów DNA, mówiąca pośrednio o cechach organizmu; nośnikiem informacji genetycznej jest DNA

genetic code
genetic code
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Nagranie dźwiękowe słówka genetic code

kod genetyczny – sposób zapisu informacji genetycznej w materiale genetycznym (DNA)

codon
codon
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Nagranie dźwiękowe słówka codon

kodon – trójka kolejnych nukleotydów w sekwencji kwasu nukleinowego, kodująca jeden aminokwas

nucleotide sequence
nucleotide sequence
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Nagranie dźwiękowe słówka nucleotide sequence

sekwencja nukleotydów – kolejność ułożenia nukleotydów w cząsteczce DNA